详细资料
个人经历
教育经历
1979/09-1983/07，厦门大学，植物学，理学学士
1983/09-1986/09，厦门大学，生化遗传，理学硕士，导师：黄厚哲
1991/09-1995/09，美国肯塔基大学，植物分子生物学/生物化学，哲学博士，导师：ArthurG.Hunt
1995/10-1996/09，美国肯塔基大学，植物生理/分子生物学，博士后，导师：ArthurG.Hunt
工作经历
1986/09-1988/11，厦门大学，生物系，助教
1989/12-1991/09，厦门大学，生物系，讲师
1996/09-2001/07，美国肯塔基大学，烟草研发中心，研究员
2001/08-2007/06，美国迈阿密大学，植物学系，助理教授
2007/07-2010/06，美国迈阿密大学，植物学系，副教授（Tenured）
2010/07-2015/06，美国迈阿密大学，植物学系（后为生物学系），教授
2012/09-至今，厦门大学，环境与生态学院院长，教授
研究方向
植物mRNA多聚腺苷化的分子生物学（PlantmRNAPolyadenylation）
红树植物环境适应性的分子生态学（MolecularEcologyofMangroveAdaption）
生物信息学（Bioinformatics）
主讲课程
分子生物学基础，分子生态学，遗传与进化，生态之美，环境与生态组学技术
MolecularBiology,MolecularEcology,GeneticandEvolution,BeautyofEcosystem,OmicTechnologiesinEnvironmentandEcology
学术成果
环境适应性及分子生态学研究
1.JunjieYin,MingZhou,ZeruLin,QingshunQ.Li,Yuan-YeZhang*.2019.Transgenerationaleffectsbenefitoffspringacrossdiverseenvironments:ameta‐analysisinplantsandanimals.EcologyLetters,22:1976–1986.
2.HongmeiQiao,WenwenLiu,YihuiZhang*,YuanyeZhang*,QingshunQ.Li*.2019.Geneticadmixtureacceleratesinvasionviaprovisioningrapidadaptiveevolution,MolecularEcology.28:4012-4027.
3.WenyueSu,CongtingYe,YihuiZhang,SaiqiHao,QingshunQ.Li*.2019.IdentificationofputativekeygenesforcoastalenvironmentsandcoldadaptationinmangroveKandeliaobovatathroughtranscriptomeanalysis.ScienceoftheTotalEnvironment.681:191–201.DOI:10.1016/j.scitotenv.2019.05.127
4.LiweiHong,WenyueSu,YuanyeZhang,CongtingYe,YingjiaShen,QingshunQ.Li*.2018.Transcriptomeprofilingduringmangroveviviparityinresponsetoabscisicacid.ScientificReports,8:770.DOI:10.1038/s41598-018-19236-x.
5.LiweiHong,LiangjieZhang,MeilingLiu,ShengjieWang,LinjunHe,WanyuYang,JingliLi,QiaojieYu,QingshunQ.Li*&KefuZhou*.2018.Heavymetalrichstone-processingwastewaterinhibitsthegrowthanddevelopmentofplants.InternationalJournalofPhytoremediation.21:5,479-486,DOI:10.1080/15226514.2018.1537241
6.NezaRepar,HaoLi,JoseS.Aguilar,QingshunQ.Li,DrobneDamjana,andYilingHong*.2018.Silvernanoparticlesinduceneurotoxicityinahumanembryonicstemcell-derivedneuronandastrocytenetwork.Nanotoxicology,12:104-116.DOI:10.1080/17435390.2018.1425497
7.LuzhenChen*,WenqingWang,QingshunQ.Li,YihuiZhang,ShengchangYang,MichaelJ.Osland,JinliangHuang,andCongjiaoPeng.2017.Mangrovespecies’responsestowinterairtemperatureextremesinChina.Ecosphere,8(6):e01865.DOI:10.1002/ecs2.1865
8.Xiao-xuanZhou,Ling-lingCai,Mei-pingFu,Li-weiHong,Ying-jiaShen,QingshunQ.Li*,2016.ProgressintheStudiesofViviparyonMangrovePlants.ChineseJournalofPlantEcology40(12):1328-1343.周晓旋,蔡玲玲,傅梅萍,洪礼伟,沈英嘉,李庆顺*.2016.红树植物胎生现象研究进展,植物生态学报,40(12):1328-1343.(InChinesewithEnglishabstract)Doi:10.17521/cjpe.2016.0087.
mRNA多聚腺苷化机理机制与生物信息学研究
9.ZhiboYu,JunchengLin,QingshunQ.Li*.2019.TranscriptomeanalysesofFYmutantsrevealitsroleinmRNAalternativepolyadenylation.ThePlantCell.31(10):2332-2352.
10.HaihuiFu,PengWang,XiaohuiWu,XiaoxuanZhou,GuoliJi,YingjiaShen,YahuiGao,QingshunQ.Li*,JunrongLiang*.2019.Distinctgenome‐widealternativepolyadenylationduringtheresponsetosiliconavailabilityinthemarinediatomThalassiosirapseudonana.ThePlantJournal.99(1):67-80.DOI:10.1111/tpj.14309
11.CongtingYe,QianZhou,XiaohuiWu,GuoliJi,QingshunQ.Li.2019.Genome-widealternativepolyadenylationdynamicsinresponsetobioticandabioticstressesinrice.EcotoxicologyandEnvironmentalSafety.183:109485.DOI:10.1016/j.ecoenv.2019.109485.
12.CongtingYe,QianZhou,XiaohuiWu,ChenYu,GuoliJi,DanielRSaban,QingshunQ.Li.2019.scDAPA:detectionandvisualizationofdynamicalternativepolyadenylationfromsinglecellRNA-seqdata.Bioinformatics.
13.CongtingYe,QianZhou,YilingHong,QingshunQ.Li.2019.Roleofalternativepolyadenylationdynamicsinacutemyeloidleukaemiaatsingle-cellresolution.RNABiology.16:6,785-797.DOI:10.1080/15476286.2019.1586139
14.QianZhou,HaihuiFu,DeweiYang,CongtingYe,ShengZhu,JunchengLin,WenbinYe,GuoliJi,XinfuYe,XiaohuiWu*,QingshunQ.Li*.2019.Differentialalternativepolyadenylationcontributestothedevelopmentaldivergencebetweentworicesubspecies,japonicaandindica.ThePlantJournal.98,260-276.
15.JingyiCao,CongtingYe,GuijieHao,CaroleDabney-Smith,ArthurG.Hunt,QingshunQ.Li*.2019.Roothairsinglecelltypespecificprofilesofgeneexpressionandalternativepolyadenylationundercadmiumstress.FrontiersinPlantScience.
16.ZhixinZhao,XiaohuiWu,GuoliJi,ChunLiang,QingshunQ.Li*.2019.Genome-widecomparativeanalysesofpolyadenylationsignalsineukaryotessuggestapossibleoriginoftheAAUAAAsignal.InternationalJournalofMolecularSciences.20(4):958.Doi:10.3390/ijms20040958.
17.CongtingYe,YuqiLong,GuoliJi,QingshunQ.Li*,XiaohuiWu*.2018.APAtrap:identificationandquantificationofalternativepolyadenylationsitesfromRNA-seqdata.Bioinformatics,34(11):1841-1849.DOI:10.1093/bioinformatics/bty029
18.LiweiHong,CongtingYe,JunchengLin,HaihuiFu,XiaohuiWuandQingshunQ.Li*.2018.Alternativepolyadenylationisinvolvedinauxin-basedplantgrowthanddevelopment.PlantJournal,93:246-258.doi:10.1111/tpj.13771.
19.JunchengLin,RuqiangXu,XiaohuiWu,YingjiaShenandQingshunQ.Li*.2017.Roleofcleavageandpolyadenylationspecificityfactor100:anchoringpoly(A)sitesandmodulatingtranscriptiontermination.PlantJournal,91:829–839.DOI:10.1111/tpj.13611
20.ChengGuo,MatthewSpinelli,CongtingYe,QingshunQ.Li*andChunLiang*.2017.Genome-WideComparativeAnalysisofMiniatureInvertedRepeatTransposableElementin19ArabidopsisthalianaAccessions.ScientificReports,7:2634.DOI:10.1038/s41598-017-02855-1.
21.QingshunQ.Li*,ZhaoyangLiu,WenjiaLuandManLiu.2017.InterplaybetweenAlternativeSplicingandAlternativePolyadenylationDefinestheExpressionOutcomeofthePlantUniqueOXIDATIVETOLERANT-6Gene.ScientificReports,7:2052.DOI:10.1038/s41598-017-02215-z
22.HaihuiFu,DeweiYang,WenyueSu,LiuyinMa,YingjiaShen,GuoliJi,XinfuYe*,XiaohuiWu*,QingshunQ.Li*.2016.Genome-wideDynamicsofAlternativePolyadenylationinRice.GenomeResearch,26:1753-1760.Doi:10.1101/gr.210757.116
23.XiaohuiWu*,YuminZhang,QingshunQ.Li*.2016.PlantAPA:aportalforvisualizationandanalysisofalternativepolyadenylationinplants.FrontiersinPlantScience,7:889.doi:10.3389/fpls.2016.00889.
24.ChengGuo,MatthewSpinelli,ManLiu,QingshunQ.Li*andChunLiang*.2016.AGenome-wideStudyof"Non-3UTR"PolyadenylationSitesinArabidopsisthaliana.ScientificReport,6:28060;doi:10.1038/srep28060(2016).
25.XiaohuiWu*,YongZeng,JintingGuan,Guoli,Ji,RongtingHuang,QingshunQ.Li*.2015.Genome-wideCharacterizationofIntergenicPolyadenylationSitesRedefinesGeneSpacesinArabidopsisthaliana.BMCGenomics.16:511.DOI:10.1186/s12864-015-1691-1
26.GuoliJi,JintingGuan,YongZeng,QingshunQ.LiandXiaohuiWu*.2015.Genome-wideidentificationandpredictivemodelingofpolyadenylationsitesineukaryotes.BriefingsinBioinformatics.16(2):304-313.DOI:10.1093/bib/bbu011
27.GuoliJi,LeiLi,QingshunQ.Li,XiangdongWu,JingyiFu,XiaohuiWu*.2015.PASPA:awebserverformRNApoly(A)sitepredictionsinplantsandalgae.Bioinformatics,31(10):1671-3.doi:10.1093/bioinformatics/btv004.
28.JintingGuan,JingyiFu,MingchengWu,LongtengChen,GuoliJi,QingshunQ.Li,XiaohuiWu*.2015.VAAPA:Awebplatformforvisualizationandanalysisofalternativepolyadenylation.ComputBiolMed.57:20-25.doi:10.1016/j.compbiomed.2014.11.010
29.ManLiu,RuqiangXu,CarrieMerrill,LiweiHong,CarolVonLanken,ArthurG.Hunt*andQingshunQ.Li*.2014.Integrationofdevelopmentalandenvironmentalsignalsviaapolyadenylationfactorinplants.PloSOne.9:e115779.doi:10.1371/journal.pone.0115779.
30.XiaohuiWu,BobbyGaffney,ArthurG.Hunt*,andQingshunQ.Li*.2014.Genome-widedeterminationofpoly(A)sitesinMedicagotruncatula:evolutionaryconservationofalternativepoly(A)sitechoice.BMCGenomics.15:615.DOI:10.1186/1471-2164-15-615.
31.ZhixinZhao,XiaohuiWu,PraveenKumarRajKumar,MinDong,GuoliJi,QingshunQ.Li*andChunLiang*.2014.BioinformaticsanalysisofalternativepolyadenylationingreenalgaChlamydomonasreinhardtiiusingtranscriptomesequencesfromthreedifferentsequencingplatforms.GenesGenomicsGenetics(G3).4:871-883.DOI:10.1534/g3.114.010249
32.LiuyinMa,PratapKumarPati,ManLiu,QingshunQ.Li*andArthurG.Hunt*.2014.Highthroughputcharacterizationsofpoly(A)sitechoiceinplants.Methods.67:74-83.
33.LiuyinMa,ChengGuoandQingsunQ.Li*.2014.Roleofalternativepolyadenylationinepigeneticsilencingandantisilencing.Proc.Nat.Acad.Sci.USA,111:9-10.DOI:10.1073/pnas.1321025111
34.WilliamCRay*,SamuelLWolock,NicholasWCallahan,MinDong,QingshunQ.Li,ChunLiang,ThomasJ.MaglieryandChristopherW.Bartlett.2014.AddressingtheunmetneedforvisualizingConditionalRandomFieldsinBiologicalData.BMCBioinformatics.15:202.
35.GuoliJi*,YongZeng,JintingGuan,QingshunQ.Li,CongtingYe,YunlongLiu.2013.RecentadvancesinmathematicalmodelingandsimulationofDNAreplicationprocess.CurrentBioinformatics.8:591-602.DOI:10.2174/15748936113088880005
36.DenghuiXing,YajunWang,RuqiangXu,XinfuYe,DeweiYang,QingshunQ.Li*.2013.TheRegulatoryRoleofPcf11-Similar-4(PCFS4)inArabidopsisDevelopmentbyGenome-WidePhysicalInteractionswithTargetLoci.BMCGenomics.14:598.DOI:10.1186/1471-2164-14-598
37.PatrickE.Thomas,XiaohuiWu,ManLiu,BobbyGaffney,GuoliJi,QingshunQ.LiandArthurG.Hunt*.2012.Genome-widecontrolofpoly(A)sitechoicebyCPSF30inArabidopsis.PlantCell.24:4376-4388.DOI:10.1105/tpc.112.096107
38.ArthurG.Hunt,DenghuiXing*,QingshunQ.Li*.2012.Plantpolyadenylationfactors:conservationandvariety.BMCGenomics.13:641.DOI:10.1186/1471-2164-13-641
39.XiaohuiWu,GuoliJi*,QingshunQ.LiandSunZhou.2012.ComprehensiverecognitionofmessengerRNApolyadenylationpatternsinplants.Afr.J.Biotech,11:3215-3234.DOI:10.5897/AJB10.2539
40.HongweiZhao,JunZheng,QingshunQ.Li*.2011.Anovelplantinvitroassaysystemforpre-mRNAcleavageandpolyadenylation.PlantPhysiology,157:1546-1554.DOI:10.1104/pp.111.179465
41.YingjiaShen,R.C.Venu,KanNobuta,XiaohuiWu,VarunNotibula,CaghanDemirci,BlakeCMeyers,Guo-LiangWang,GuoliJi,QingshunQ.Li*.2011.TranscriptomeDynamicsThroughAlternativePolyadenylationinDevelopmentalandEnvironmentalResponsesinPlantsRevealedbyDeepSequencing.GenomeResearch,21:1478-1486.DOI:10.1101/gr.114744.110
42.XiaohuiWu,ManLiu,BruceDownie,ChunLiang,GuoliJi,QingshunQ.Li*,ArthurHunt*.2011.Thegenome-widelandscapeofpolyadenylationinArabidopsisprovidesevidenceforextensivealternativepolyadenylation.Proc.Nat.Acad.Sci.USA,108:12533–12538.doi/10.1073/pnas.1019732108
43.JiantiZheng,DenghuiXing,XiaohuiWu,DianaKroll,YingjiaShen,GuoliJi,QingshunQ.Li*.2011.Ratio-basedanalysisofdifferentialmRNAprocessingandexpressionofapolyadenylationfactormutantpcfs4usingArabidopsistilingmicroarray.PLoSOne,6:e14719.DOI:10.1371/journal.pone.0014719
44.DenghuiXing,QingshunQ.Li*.2011.Alternativepolyadenylationandgeneexpressionregulationinplants.WIREs(WilleyInterdisciplinaryReviews)RNA,2:445-458.(Invitedreview)DOI:10.1002/wrna.59
45.GuoliJi,XiaohuiWu,YingjiaShen,JiangyinHuangandQingshunQ.Li*.2010.AClassification-BasedPredictionModelsofMessengerRNAPolyadenylationSites.JournalofTheoreticalBiology,265:287-296.DOI:10.1016/j.jtbi.2010.05.015
46.GuoliJi*,XiaohuiWu,JiangyinHuang,QingshunQ.Li.2010.ImplementationofaClassification-BasedPredictionModelforPlantmRNAPoly(A)Sites.JournalofComputationalandTheoreticalNanoscience,7(5):927-932.DOI:10.1166/jctn.2010.1440
47.HongweiZhao,DenghuiXing,QingshunQ.Li*.2009.Uniquefeaturesofplantcleavageandpolyadenylationspecificityfactorrevealedbyproteomicstudies.PlantPhysiology,151:1546-1556.DOI:10.1104/pp.109.142729
48.DenghuiXing,HongweiZhaoandQingshunQ.Li*.2008.ArabidopsisCLP1-SimilarProtein3,anorthologofhumanpolyadenylationfactorCLP1,functionsingametophyte,embryoandpost-embryonicdevelopment.PlantPhysiology,148:2059-2069.doi/10.1104/pp.108.129817
49.YingjiaShen,YuanshengLiu,LinLiu,ChunLiang,andQingshunQ.Li*.2008.UniquefeaturesofnuclearmRNApoly(A)signalsandalternativepolyadenylationinChlamydomonasreinhardtii.Genetics,179:167-176.DOI:10.1534/genetics.108.088971
50.DenghuiXing,HongweiZhao,RuqiangXuandQingshunQ.Li*.2008.ArabidopsisPCFS4,ahomologueofyeastpolyadenylationfactorPcf11p,regulatesFCAalternativeprocessingandpromotesfloweringtime.PlantJournal,54:899-910.DOI:10.1111/j.1365-313X.2008.03455.x
51.ArthurG.Hunt*,RuqiangXu,BalasubrahmanyamAddepalli,SuryadevaraRao,KevinP.Forbes,LisaR.Meeks,DenghuiXing,MinMo,HongweiZhao,AmritaBandyopadhyay,LavanyaDampanaboina,AmandaMarion,CarolVonLanken,andQingshunQ.Li*.2008.ArabidopsismRNApolyadenylationmachinery:comprehensiveanalysisofprotein-proteininteractionsandgeneexpressionprofiling.BMCGenomics,9:220.DOI:10.1186/1471-2164-9-220HighlyAccessed
52.YingjiaShen,GuoliJi,BrianJ.Haas,XiaohuiWu,JiantiZheng,GregJ.Reese,andQingshunQ.Li*.2008.GenomelevelanalysisofricemRNA3’-endprocessingsignalsandalternativepolyadenylation.NucleicAcidsResearch,36:3150-3161.DOI:10.1093/nar/gkn158
53.JingxianZhang,Kil-YoungYun,RuqiangXu,ArthurG.Hunt,IrinaArtiushin,KimDelaney,QingshunQ.LiandDeaneL.Falcone*.2008.APolyadenylationFactorSubunitImplicatedinRegulatingOxidativeSignalinginArabidopsisthaliana.PLoSOne,3:e2410.DOI:10.1371/journal.pone.0002410
54.ChunLiang*,YuanshengLiu,LinLiu,AdamC.Davis,YingjiaShen,andQingshunQ.Li.2008.ExpressedsequencetagswithcDNAtermini–previouslyoverlookedresourcesforgeneannotationandtranscriptomeexplorationinChlamydomonasreinhardtii.Genetics,179:83-93.DOI:10.1534/genetics.107.085605
55.GuoliJi,JiantiZheng,YingjiaShen,XiaohuiWu,RonghanJiang,YunLin,JohnnyC.Loke,KimberlyM.Davis,GregJ.ReeseandQingshunQ.Li*.2007.PredictivemodelingofplantmessengerRNApolyadenylationsites.BMCBioinformatics,8:43.DOI:10.1186/1471-2105-8-43HighlyAccessed
56.GuoliJi,XiaohuiWu,JiantiZheng,YingjiaShenandQingshunQ.Li*.2007.ModelingPlantmRNAPoly(A)sites:SoftwareDesignandImplementation.JournalofComputationalandTheoreticalNanoscience,4:1365-1368.DOI:10.1166/jctn.2007.025
57.KimDelaney,RuqiangXu,JingxianZhang,QingshunQ.Li,Kil-YoungYun,DeaneL.FalconeandArthurG.Hunt*.2006.CalmodulininteractswithandregulatestheRNA-bindingactivityofanArabidopsispolyadenylationfactorsubunit.PlantPhysiology,140:1507-1521.DOI:10.1104/pp.105.070672
58.BalasubrahmanyamAddepalli,RuqiangXu,TomalDattaroy,BaochunLi,W.TroyBass,QingshunQ.LiandArthurG.Hunt*.2006.Diseaseresistanceinplantsthatcarryafeedback-regulatedyeastpoly(A)bindingproteingene.PlantMolecularBiology,61:383-397.DOI:10.1007/s11103-006-0019-6
59.RuqiangXu,HongweiZhao,RandyDinkins,XiaowenCheng,GeorgeCarberryandQingshunQ.Li*.2006.The73kDsubunitofthecleavageandpolyadenylationspecificityfactor(CPSF)complexaffectsreproductivedevelopmentinArabidopsis.PlantMolecularBiology,61:799-815.DOI:10.1007/s11103-006-0051-6
60.JohnnyC.Loke,EricStahlberg,DaveStrenski,BrianJ.Haas,P.ChrisWoodandQingshunQ.Li*.2005.CompilationofmRNAPolyadenylationSignalsinArabidopsisRevealedaNewSignalElementandPotentialSecondaryStructures.PlantPhysiology,138:1457-1468.DOI:10.1104/pp.105.060541
其他
61.DeweiYang,XinfuYe*,XianghuaZheng,ChaopingCheng,NingYe,LibinLu,FenghuangHuang,QingshunQ.Li*.2016.IdentificationandfinemappingofLD1,asinglerecessivegeneplayinganessentialroleinthedevelopmentoflemmainrice.J.AgriculturalScience154(6)989-1001.DOI:10.1017/S0021859615000866
62.DavidA.Francko*,KennethG.Wilson,QingshunQ.LiandAlejandraEquiza.2011.Atopicalspraytoenhanceplantresistancetocoldinjuryandmortality.HortTechnology,21:109-118.
63.DenghuiXing,ShuisongNi,MichaelA.Kennedy,QingshunQ.Li*.2009.Identificationofaplant-specificZn-sensitiveribonucleaseactivity.Planta,230:819-825.DOI10.1007/s00425-009-0986-3
64.RuqiangXuandQingshunQ.Li*.2008.StreamlinecloningofgenesintobinaryvectorsinAgrobacteriumviatheGateway?TOPOvectorsystem.PlantMethods,4:4.DOI:10.1186/1746-4811-4-4
65.HongyanXing,OrlandoChambers,ChrisB.Lawrence,H.MaelorDavies,NicholasP.EverettandQingshunQ.Li*.2006.Increasedpathogenresistanceandyieldintransgenicplantsexpressingcombinationsofthemodifiedantimicrobialpeptidesbasedonindolicidinandmagainin.Planta,223:1024-1032.DOI:10.1007/s00425-005-0143-6