1992-1996扬州大学学士
2000-2005浙江大学博士
2006-2010美国国立卫生研究院NIH,美国国家癌症研究所NCI,PostdoctoralFellow
2010-2011美国国立卫生研究院NIH,美国国家癌症研究所NCI,ResearchFellow
2011-至今清华大学生命科学学院研究员,博导
长期从事基因打靶和表观遗传学研究。通过运用模式生物,结合遗传、生化和生物大数据分析,研究染色质遗传与表观遗传因子(如非编码RNA和组蛋白密码)在发育、生殖、天然免疫、衰老和癌症等疾病过程中的生物学功能及分子调控网络。[1-4]
(已发表30余篇具有较高影响因子的SCI论文)
1.WenK#,YangL#,XiongT#,DiC,MaD,WuM,XueZ,ZhangX,LongL,ZhangJ,BiX,DaiJ,ZhangRenM,LongL,ZhangQ,LuZJ.&GaoG*.CriticalrolesoflongnoncodingRNAsinDrosophilaspermatogenesis.GenomeResearch.2016Sep;2(通讯作者;被F1000推荐阅读)[1-2]
2.XiaoX#,YangL#,PangX#,ZhangR,ZhuY,WangP,GaoG*&ChengG*.AMesh-Duoxpathwayregulateshomeostasisintheinsectgut.NatureMicrobiology.2017Mar1;2:17020(通讯作者)
3.GersteinMB,Rozowsky,YanKK…GaoG…WaterstonR*.Comparativeanalysisofthetranscriptomeacrossdistantspecies.Nature.2014Aug28;512(7515):445-448.4.XueZ,WuM,WenK,RenM,LongL,ZhangX.&GaoG*.CRISPR/Cas9MediatesEfficientConditionalMutagenesisinDrosophila.G3:Genes|Genomics|Genetics.2014Sep5.pii:g3.114.014159.(通讯作者;2014highlightinGSA)
5.XueZ,RenM,WuM,DaiJ,RongYS.&GaoG*.Efficientgeneknock-outandknock-inwithtransgenicCas9inDrosophila.G3:Genes|Genomics|Genetics.2014Mar21;4(5):925-9.(通讯作者;2014highlightinGSA)
6.WeiW,XinH,RoyB,DaiJ,MiaoY*&GaoG*.HeritablegenomeeditingwithCRISPR/Cas9inthesilkworm,Bombyxmori.PLoSOne.2014Jul11;9(7):e101210.(通讯作者)
7.YuZ#,RenM#,WangZ,ZhangB,RongYS,JiaoR*&GaoG*.HighlyefficientgenomemodificationsmediatedbyCRISPR/Cas9inDrosophila.Genetics.2013Sep;195(1):289-91.(通讯作者;2013highlightinGSA)
8.Gao,G.J.,Chen,Y.,Wesolowska,N.&Rong,YK*.ApaternalimprintfortheinheritanceoftelomereidentityinDrosophila.PNAS.2011Mar22;108(12):4932-7.
9.Gao,G.J.,WalseJ.,Michelle,B.,Patrizia,M.,Natalia,W.,Chen,J.&Rong,YK*.HipHopinteractswithHOAPandHP1toprotectDrosophilatelomeresinasequence-independentmanner.EMBOJ.2010,Feb17;29(4):819-29.
10.Gao,G.J#.,Bi,X#.,Chen,J.,Srikanta,D.&Rong,YK*.Mre11-Rad50-NbscomplexisrequiredtocaptelomeresduringDrosophilaembryogenesis.PNAS.2009,Jun30;106(26):10728-33.
11.Gao,G.J.,Conor,M.,Chen,J.&Rong,YK*.Apowerfulmethodcombininghomologousrecombinationandsite-specificrecombinationfortargetedmutagenesisinDrosophila.PNAS.2008,Sep16;105(37):13999-4004.